The invention relates to novel formula of heterochrome ketone-4 derivatives, and its pharmaceutical acceptable salt. In which R1 said hydrogen or C1 to C8 of linear or branched alkyl chain, R2, R3 same or different, said hydrogen or C1 to C8 straight or branched chain alkyl or C1 to C8 acyl. The invention also involved in the preparation of compounds, the drug combinations with active ingredient of this compounds, as well as the application of this compounds and medicinal combinations in the treatment of hypertension. |