| Original document(23 pages) Authorized document(23 pages) 中文版 |
The present invention relates to a human functional gene, especially CR-1 gene related to cell reconstitution, conduction and death. The gene is obtained through the comprehensive technological process of cDNA selection, EST location, genome DNA sequence analysis, PCR reaction and cloning end expanding, etc. Experiments including Northern and Western cross breeding detection of CR-1 gene expression in tumor cell, RNA interference immunohitochemistry detection of the expressino of CR-1 in myocardial tissue of myocardial disease patient, systemic research of the expression of CR-1 interacted protein and CR-1 gene in coliform bacteria and euaryotice cell, etc. show that the gene may be used as the target site in clinical diagnosis and treatment of myocardial disease and tumors. |
Application Number
申请号 |
02153656 |
Application Date
申请日 |
2002.12.03 |
| Title 名称 |
CR1 gene related to cell reconstitution, conduction and death
|
Publication Number
公开号 |
1417223 |
Publication Date
公开日 |
2003.05.14 |
| Approval Pub. Date |
|
Granted Pub. Date |
2005.11.09 |
| International Classification 分类号 |
C12N15/12,C12N15/11,C12N15/63,C12Q1/68,C07K16/18,A61K39/395,G01N33/574,A61P35/00,A61P9/00 |
Applicant(s) Name
申请人 |
Inst. of Medicinal Biotechnology, Chinese Academy of Medicinal Sciences |
| Address 地址 |
100050 |
| Inventor(s) Name 发明人 |
Wang Yiguang, Li Tianbo |
| Attorney & Agent 代理人 |
yang hou wang wei |
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