The present invention relates to a tanshinone solid dispersion and its preparation method. It uses polyvinyl pyrrolidone (PVP) and low viscosity ethyl cellulose (EC) as combined carrier, ethyl alcohol as solvent, and adopts spray-drying method to prepare tanshinone solid dispersion. The tanshinone in amorphous state is made highly disperse in the combined carrier, and further by regulating the ratio of EC and PVP to adjust the releasing speed of tanshinone to attain the result of both quick effect and slow-release, and by regulating the spray-drying condition to obtain ball-shaped powder particles with good fluidity. |