The present invention relates to structure formula I and structure formula II ginsenoside aglycone derivative dammar-3 beta, 12 beta-dihydroxyl-20(21), 24(25)-diene, called delta 20(21)-PPD for short and dammer-3 beta, 6 alpha, 12 beta-trihydroxyl-20(21), 24(25)-diene, called delta 20(21)-PPT, specially, relates to novel anti-tumor preparation using delta 20(21)-PPD or/and delta 20(21)-PPT and containing delta 20(21)-PPD or/and delta 20(21)-PPT as active component. The delta 20(21)-PPD and delta 20(21)PPT have the anti-tumor activity of inducing tumor cell differentiation, inducing tumor cell dauth, inhibiting tumor growth, reversing tumor drugs-resistance, inhibiting tumor nascent angiogenesis, inhibiting infiltration and metastasis of tumor and raising immunity of human body, etc. |