| Original document(12 pages) 中文版 |
The invention relates to a gene compound method of accelerating animals' growth and a eucaryon expression carrier construted. Genes relating to growing includes genes anastomosing hepatitis B surface antigen (HBsAg) with growth hormone releasing factor GRF(1-32) and growth hormone release inhibiting hormone SS; its compound not only anastomoses GRF(1-32) with SS-HBsAg and constructs a expression plasmid pIRES-GRF-HBsAg-SS��Or clone said compound to viral vectors relating to adenovirus. Injecting plasmids to animal muscular tissues through exposed plasmids and PLGA microballoon wrappings can both accelerate the growth of nimals. The growth promoting effect of double genes combination is better than single gene, PLGA microballoon wrappings could enhance gene-expression level to achieve better injection effect compared with exposed plasmids. Said invention offers a new effective method of accelerating animals' growth by genetransfer techniques. |
Application Number
申请号 |
200510017154 |
Application Date
申请日 |
2005.09.23 |
| Title 名称 |
GRF��1-32��and SS-HbsAg fusion gene combination and its constructed expression system and pharmaceutical preparation
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Publication Number
公开号 |
1769453 |
Publication Date
公开日 |
2006.05.10 |
| Approval Pub. Date |
|
Granted Pub. Date |
|
| International Classification 分类号 |
C12N15/12,C12N15/62,C12N15/63,A61K48/00 |
Applicant(s) Name
申请人 |
Zhang Yongliang |
| Address 地址 |
130021 |
| Inventor(s) Name 发明人 |
Zhang Yongliang, Liu Songcai, Dai Jianwei |
| Attorney & Agent 代理人 |
chen hongwei |
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